??? ????? ????? ?? ???? ??? ?? ??????????? ?? ???????? ???? ?? ????? ?? ???? ??? ????? ??? ??? ???? ??????????? ?????????: ?????? ?? ???? ?? ??? ???? ?? ??? ???????? ?? ????? ???? ?? ???? ??? ???????? ?? ????? ?? ????? ?? ?????? ???? ???, ????? ?????? ?? ???? ?? ???? ???Exploration may well include allocating patients to distinct treatment teams; c